Biocomputer Science 1400-216BINF

1. Introduction to bioinformatics. Databases for molecular biology and biotechnology- review.
2. Basic operations. Searching databases with keywords.
3. Alignment of two nucleotide/protein sequences. Searching databases Rusing sequence as a query..
4. Multiple sequence alignment. Analysis of protein familie, family representations, profile searches.
5. Sequence motifs. Motifs of sequence familie, sorting signals, sequences controlling gene expression.
6. Finding coding and non-coding DNA regions.
7. Molecular evolution
8. Sequence Retrieval System .
9. PDB structural database. Molecular graphics.
10. Modelling protein structures.
11. Tools available online.
12. Solution of exemplary, complex problem