Radiochemistry 1100-3BF15

1. History and evolution of isotopic methods. Production of radioisotopes.
2. γ emitters. Single photon emission computed tomography (SPECT). Characteristics of the method. Applications. Review and application of basic radiopharmaceuticals based on γ emitters. (3h)
3. β emitters. Positron emission tomography (PET). Characteristics of the method. Applications.
4. Radiochemistry C11. Review and application of basic radiopharmaceuticals based on the C11.
5. F18 radiochemistry. Review and application of basic radiopharmaceuticals based on the F18.
6. O15 radiochemistry. Long-lived isotopes.
7. therapeutic radiopharmaceuticals
8. Fundamentals of pharmaceutical technology. Design of radiopharmaceuticals. Preparation of radiopharmaceuticals.
9. Good Manufacturing Practice
10. Quality control of radiopharmaceuticals.
11th Legislation.

Course coordinators

Małgorzata Leszczyńska

Mode

Classroom

Prerequisites (description)

The task of the course is to familiarize students with the methods of preparation and applications of radiopharmaceuticals in diagnostics and therapy.

Bibliography

Welch M, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, Wiley, 2005
- Planning a Clinical PET Centre, IAEA Human Health Series vol.11, IAEA 2010
- Cyclotron Produced Radionuclides: Guidelines for Setting Up a Facility Details, IAEA Technical Reports Series No. 471, IAEA 2009;
- Strategies for Clinical Implementation and Quality Management of PET Tracers, IAEA 2009;