Molecular biology with genetics 1 1000-713BM1
Fundamental concepts of genetics. Genetics among other biological disciplines. A brief history of the study of heredity. Classical genetics. Mendel’s laws. Chromosomal theory of heredity. Linkage mapping. Complementation.
Methods and strategies of genetics and genomics.
Functional analysis of mutations. Genetic interactions. Interactomics in systems biology.
Replication of DNA, mutagenesis, DNA repair. Recombination.
Gene expression. Genetic switches and genetic mechanisms of development and differentiation.
Fundamental population genetics and molecular evolution. Selection and drift in the evolution of populations and sequences. Genetic information and information theory, entropy and information in sequences.
Molecular biology of prokaryotic genes and genomes.
Course coordinators
Type of course
Learning outcomes
Knowledge:
- has knowledge concerning the most important processes in plants and animals and their regulation
- observes and understand the diversity of regulatory systems in biology
Abilities and social awareness:
- presentation of the flow of genetic information and its regulation, the rules of heredity, and the fundamentals of genetic engineering
Assessment criteria
Written exam covering the knowledge presented during lectures.
Bibliography
Genomes 4. T. A. Brown. 2018
Fundamental Molecular Biology, 3rd edition, LA Allison